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Studies designed to provide insight into clinical practice in the real world are called pragmatic trials. They are usually focused on practical aspects of the study design, such as the recruitment and consent process as well as adherence to the use of standard equipment.

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While Pragmatic Play is known for its slot machines, it also offers table games such as Bitcoin baccarat and Roulette. They offer more than dozen licensed games, and their software is well-known for its security and reliability. Their software is available in a variety of languages and provide a variety of betting options, including live dealer tables.

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Pragmatic is a software company offers a range of casino games for online gambling platforms. Pragmatic's iGaming software is used by leading operators as well as land-based casinos. The company offers front-end design tools, analysis tools, marketing, promotions and payment systems, as well as security, customer support and bug reporting. The company also offers an environment that is safe and secure with high-quality graphics, games and security.

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Another example of a pragmatic trial is the Home Blood Pressure Management (HBPM) study, which used a variety of investigators and had participants from different geographic areas. This kind of heterogeneity, which is vital for pragmatic trials to be reliable and to reduce bias in the results is also essential. A high degree of heterogeneity, however could cause issues with the trial design.

Pragmatic Play is also a major player on the live casino market, offering an extensive selection of table games that are classic such as Blackjack and Roulette in various variations. Pragmatic Play's live studios in Romania and Malta offer an authentic gambling experience for customers and offer a wide range of virtual betting options. The company also hosts a variety of game shows that make online gambling exciting and interactive. Some of these shows are hosted live and others are hosted by famous personalities from the industry.

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Pragmatic Play is a new player in the online casino industry however, it has already made a name for itself through its mobile-friendly slot machines. Their games are optimized for mobile devices and are powered by HTML5 technology. They're also certified by reputable gaming authorities to ensure transparency and fairness. This is a great signal for players since it means the games have been tested and validated in order to guarantee the randomness and impartiality of every round.

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Pragmatic trials seek to replicate real-life situations and attain maximum external validity. They are typically commissioned by policy makers and practitioners to inform their decision making. They can also be used to determine the causality of an intervention with its outcomes. However, they shouldn't be used in lieu for explanation studies.

The pragmatism idea is controversial and there are questions about whether pragmatic trials should replace or complement them. Schwartz and Lellouch1 suggested the distinction between explanatory trials, which prove the clinical or physiological hypothesis, and pragmatic trials, which guide the practice and policy decisions. They also suggested a framework for pragmatic trials, called PRECIS.2 This tool was designed to define the features of a pragmatic study which includes the recruitment process, the design and delivery of the intervention, as well as follow-up.

The number of pragmatic trials is increasing. A recent Medline search using the words pragmatic and naturalistic, which was restricted to randomised controlled trials (RCTs) returned 34 articles. These are highlighted in red on Figure 2. This suggests that the health sciences community is becoming more aware of the importance of pragmatism. It is important to keep in mind that the majority of these studies were conducted in primary-care settings.