• 목록
• 답변
• 글쓰기
• 게시판 리스트 옵션
  • 수정
  • 삭제

Latest Depression Treatments

If your depression doesn't improve through psychotherapy and antidepressants new medications that respond quickly may be able to treat treatment-resistant depression.

SSRIs, or selective serotonin reuptake inhibitors are the most commonly prescribed and well-known antidepressants. These antidepressants work by altering the way the brain uses serotonin.

Cognitive behavioral therapy (CBT) helps you change negative thoughts and behaviours like hopelessness. The NHS offers 8 to 16 sessions.

1. Esketamine

In March 2019, the FDA approved a new nasal spray for depression called esketamine. (Brand name Spravato). It is derived from the anesthetic the ketamine. It has been proven to be effective in severe depression. The nasal spray is used in conjunction with an oral antidepressant in order to treat depression that has not responded to standard medication. In one study 70 percent of those with treatment-resistant depression treatment in pregnancy who were given the drug responded well which was a higher response rate than with the use of an oral antidepressant.

Esketamine is different from standard antidepressants. It increases the levels of neurotransmitters in the brain that transmit messages between brain cells. The results don't come immediately. Patients usually feel better after a few days, but the effects last longer than SSRIs and SNRIs.

Researchers believe that esketamine reduces depression symptoms through strengthening brain cell connections. In animal studies, esketamine reversed these connections that are damaged through depression and chronic stress. It also appears to promote the growth of neurons that can aid in reducing suicidal thoughts and feelings.

Esketamine is different from other antidepressants in that it is administered via nasal spray. This allows it to reach your bloodstream more quickly than oral or pill medication. It has been demonstrated in studies to lessen depression symptoms within a couple of hours. In certain instances the effects can be almost immediate.

However, the results of a study that tracked patients for 16 weeks showed that not all patients who began treatment with esketamine was in the remission phase. This is a bit disappointing, but not surprising, according to Dr. Amit Anand, an expert on ketamine who was not part of the study.

Esketamine is only available in private practice or clinical trials. It is not considered a first-line treatment for depression and Pregnancy Depression Treatment is usually prescribed only when SSRIs or SNRIs haven't been effective for a patient suffering from treatment-resistant depression. A patient's physician can determine if the condition is resistant to holistic treatment for depression and decide if the use of esketamine is beneficial.

2. TMS

TMS utilizes magnetic fields in order to stimulate brain nerve cells. It is non-invasive and does not require anesthesia or surgery. It has been shown to help patients suffering from depression who have not responded to medication or psychotherapy. It can also be used to treat obsessive-compulsive disorder (OCD) and tinnitus.

For depression, TMS therapy is typically delivered in a series of 36 daily sessions spread over six weeks. The magnetic pulses are similar to pinpricks placed on the scalp and can take a bit of getting used to. After an appointment, patients can return to work or go home. Each TMS session can last between 3.5 minutes and 20 minutes, Pregnancy Depression Treatment based on the stimulation pattern.

Researchers believe that rTMS works by altering the way that neurons communicate with each other. This process, referred to as neuroplasticity allows the brain create new connections and modify its function.

TMS is FDA approved to treat depression in situations that other treatments such as medication and talk therapy have not worked. It has also been shown to help people with tinnitus, OCD and pain. Researchers are examining whether it could also be used to treat anxiety and Parkinson's disease.

TMS has been proven to reduce depression in several studies, but not everyone who receives it benefits. It is important that you undergo a thorough psychiatric as well as medical evaluation before trying this type of treatment. TMS is not suitable for you if you have a history or a history of certain medications.

If you have been suffering from depression and aren't seeing the benefits of your current treatment plan, a conversation with your psychiatrist may be helpful. You could be eligible for a TMS trial or other forms of neurostimulation. But, you must first try several antidepressants before your insurance will cover the cost. Contact us today to set up a consultation to learn more about. Our specialists will guide you in the decision of whether TMS treatment is right for you.

3. Deep brain stimulation

A noninvasive therapy that resets the brain circuitry could be effective in just one week for patients suffering from treatment-resistant depression. Researchers have come up with new methods that permit them to deliver high-dose electromagnetic pulses to the brain in a shorter period of time and at a frequency that is more adaptable for patients.

Stanford neuromodulation therapy (SNT), which is now available at the UC Davis Department of Psychiatry and Behavioral Sciences' Advanced Psychiatric Therapeutics Clinic utilizes MRI imaging to direct electrodes that transmit magnetic pulses to specific areas of the brain. In a recent study, Mitra & Raichle found that in three quarters (or more) of patients with depression treatment without meds that the normal flow of neural activity was reversed from the anterior cortex to the anterior isola. With SNT, that flow returned to normal within a week, and coincided with the lifting of their depression.

Deep brain stimulation (DBS), an invasive procedure, may produce similar results in some patients. After several tests to determine the most appropriate placement, neurosurgeons implant one or more wires, called leads, into the brain. The leads are connected to the neurostimulator. It is implanted under the collarbone and appears like a pacemaker. The device provides an uninterrupted electric current through the leads. This alters the brain's natural circuitry, decreasing depression symptoms.

Certain psychotherapy treatments can help relieve depression symptoms, such as cognitive behavioral therapy and interpersonal therapy. Psychotherapy can be delivered in one-on-one sessions with an expert in mental health or in a group setting. Therapists may also offer Telehealth services.

Antidepressants are a key component of treatment for depression. However, in recent years, there have been remarkable advancements in the speed at which these medications work to reduce symptoms of depression. Newer drugs, such as gepirone (Exxua), esketamine (Spravato), brexanolone (Zulresso) and dextromethorphan-bupropion (Auvelity), all have been shown to work faster than older antidepressants.

Other treatments, such as electroconvulsive treatment (ECT) or repetitive transcranial magnetic stimulation (rTMS), use electric or magnetic stimuli to stimulate the brain. These are more complex procedures that require a doctor's supervision. In some cases they can cause seizures and other serious adverse side effects.

4. Light therapy

Bright light therapy involves sitting or standing in front of an artificially bright light source. This therapy has been utilized for many years to treat seasonal depression as well as major depressive disorder (SAD). Studies show that it can ease symptoms like fatigue and sadness by controlling the circadian rhythm and improving mood. It also aids people who suffer from depression that comes and goes.

Light therapy mimics sunlight, which is a crucial element of the biological clock called the suprachiasmatic nucleus (SCN). The SCN is associated with mood and light therapy may change the patterns of circadian rhythms that can contribute to depression. Light therapy can also decrease the production of melatonin and improve the function of neurotransmitters.

Some doctors are also using light therapy to treat a less severe type of depression known as winter blues, which is similar to SAD but affects fewer people and is only seen in months when there is less daylight. They recommend sitting in the light therapy device each morning for 30 minutes while awake to gain the most benefits. Contrary to antidepressants, which may take weeks to begin working and can cause adverse effects like nausea or weight gain, light therapy can produce results in just a week. It's also safe to use during pregnancy depression treatment and for those who are older.

Researchers advise against using light therapy without the supervision of a mental health professional or psychiatrist, since it can trigger manic episodes in people with bipolar disorders. It can also make sufferers feel tired during the first week of treatment because it can reset their sleep-wake patterns.

PCPs must be aware of new treatments that have been approved by the FDA however, they shouldn't neglect tried-and-true methods like antidepressants or cognitive behavioral therapy. Dr. Hellerstein told Healio that although the quest for better and newer treatments is exciting, we should be focusing on the most established treatments. He says PCPs should educate their patients on the benefits of new treatments as well as assist them in sticking to their treatment plans. This could include offering transportation to the doctor's office or setting up reminders to take medication and attend therapy sessions.