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Pulmonary embolism (PE) is the leading trigger of in-hospital loss of life and the third most frequent cause of cardiovascular dying. The clinical presentation of PE is variable, and selecting the suitable therapy for individual patients can be challenging. Traditionally, treatment of PE has concerned a selection of anticoagulation, thrombolysis or surgery; however, a variety of percutaneous interventional technologies have been developed which are under investigation in patients with intermediate-high-danger or excessive-threat PE. These interventional technologies embrace catheter-directed thrombolysis (with or without ultrasound help), aspiration thrombectomy and combos of the aforementioned rules. These interventional treatment choices would possibly result in a extra fast enchancment in right ventricular function and pulmonary and/or systemic haemodynamics particularly patients.